Biopsy Drill

Liquid nitrogen biopsy drillOur biopsy drill is designed to capture a tissue sample using either liquid nitrogen or heat sink capture methods.

Using the liquid nitrogen capture method, the sample is cored out with a hollow drill. A Dewar flask or equivalent is internally chilled with liquid nitrogen and the lid is replaced while continuously being evacuated to remove the nitrogen gas evaporating from the liquid. An alternative is to pre-cool 2-methyl butane and use that as the freezing medium. The cored sample is instantaneously pulled into the flask and frozen directly in the liquid nitrogen or 2-methyl butane.

Using the heat sink capture method, the drill deposits the sample into a continuously evacuated chamber with an aluminum tissue strainer, and immediately freezes the sample on a heat sink (previously pre-cooled with liquid nitrogen). The tissue strainer is a thin-walled aluminum cup with its open end toward the drill tip. The strainer fits into the freezing compartment which in turn is firmly attached with quick removal clamps to the plastic interface.

The rotating drill allows ease of penetration into tissue, allowing comparatively longer biopsies with drills of smaller diameter. Drills are available in 2mm, 3mm, and 4mm inside diameters. Drill bits are 30mm long in standard length.

As a source of propulsion for the air motor, nitrogen is preferred to avoid introducing air moisture into the drill unit. The unit runs well at 60 to 90 PSI, and uses less than 2.5 CFM. The operating sound level has been measured at approximately 90 db for a one to two second duration.

A vacuum pump with appropriate trapping is needed. 1.4 CFM @ 20" Hg or 2.2 CFM @ 15" Hg should be adequate for the heat sink model.

Disclaimer: This unit is not intended or sold for use in vivo on humans, but only for animal research on laboratory animals. We accept no responsibility for uses outside of those for which it was sold.

Heat sink biopsy drill

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